Primary malignant non-Hodgkin's lymphomas of salivary glands.
نویسندگان
چکیده
We evaluated the medical record of patients with salivary gland neoplasms diagnosed at Timisoara City Hospital from 2002 to 2009. A study has been carried out for seven years on 204 cases of salivary gland tumors and only two cases of salivary gland lymphomas were diagnosed. The two cases were females of 71- and 49-year-old, respectively. The formalin-fixed paraffin-embedded tissue samples were cut in 4 mum thick sections and stained with Hematoxylin and Eosin. The primary monoclonal antibodies for the immunohistochemical analysis were the followings: LCA (2B11, Dako), CD20 (L26, Dako), cytokeratin (MNF116, Dako), p53 (DQ-7, Dako), and PCNA (PC-10, Dako). The histopathology and immunohistochemistry suggested in the first case a low-grade diffuse large B-cell mucosa associated lymphoid tissue lymphoma and in the second case a high-grade extranodal marginal zone B-cell lymphoma.
منابع مشابه
Oral non-squamous malignant tumors; diagnosis and treatment.
Some 90% of oral cancers consist of squamous cell carcinomas that arise from the oral mucosa. The remaining 10% of malignancies consist of malignant melanomas, carcinomas of the intraoral salivary glands, sarcomas of the soft tissues and the bones, malignant odontogenic tumors, non-Hodgkin's lymphomas and metastases from primary tumors located elsewhere in the body. These malignancies will be b...
متن کاملIncidence of invasive cancers following squamous cell skin cancer.
The authors describe the incidence of new primary cancers among 4,639 cases of squamous cell skin cancer (SCC) diagnosed between 1974 and 1994 in the cancer registries of the Swiss cantons of Vaud and Neuchâtel (total person-years at risk = 23,152). Overall, 729 metachronous cancers were observed versus 527.6 expected, corresponding to a standardized incidence ratio (SIR) of 1.4 (95% confidence...
متن کاملA Case of Primary Aggressive Non Hodgkin’s Lymphoma of Parotid Gland
Primary lymphomas arising from the parotid gland are uncommon and usually account for only 0.6–5% of tumors or tumor-like lesions of the parotid, and therefore are commonly overlooked. Most cases involve the major salivary glands, primarily the parotid (50-93%) and the submandibular glands [1]. The misdiagnosis often leads to unnecessary diagnostic procedures thereby delaying the initiation of ...
متن کاملPrimary Large B-Cell Lymphoma of the Base of Tongue
Non-Hodgkin lymphoma (NHL) represents the third most common group of malignant lesions of the oral cavity, following squamous cell carcinomas and salivary gland neoplasms. It accounts for 3-5% of all malignant lesions of the oral cavity [1]. Further, only 1% of all lymphomas are primary oral cavity lymphoma. Non-Hodgkin’s lymphoma of the tongue is extremely rare. It can arise from Waldeyer’s ri...
متن کاملPrelymphoma, early lymphoma, and manifest lymphoma in immunosialadenitis (Sjögren's syndrome)--a model of lymphomagenesis.
The development of malignant lymphoma in myoepithelial sialadenitis with and without Sjögren's syndrome was investigated. At first, prelymphomatous proliferation areas showing a polytypic immunoglobulin (Ig) pattern were seen. These transformed into malignant lymphoma with a monotypic Ig pattern, at first in small, circumscribed proliferation areas ("early lymphoma") and later in large, conflue...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
دوره 50 4 شماره
صفحات -
تاریخ انتشار 2009